Between 30 and 60% of the population have experienced sense of presence in the form of a deceased loved one (Castelnovo et al., 2015; Elsaesser et al., 2021; Streit-Horn, 2011). These experiences (i.e., ghosts, grief or bereavement hallucinations) may generally be called after death experiences (ADEs). In this paper, I will argue that 4E cognition, or the notion that cognition is shaped by dynamic interactions between the brain, body, and physical/social environments, plays a key role in understanding the cognitive underpinnings and behavioral outcomes of ADEs as both universal experiences and those deemed religious or spiritual. Drawing from mixed-methods experimental research in cognitive neuroscience, I posit that sensorimotor manipulations of a bereaved individual may induce experiences of presence more readily than in non-bereaved. Based on clinical data and preliminary findings, I will explore how future research relying on 4E cognition principles may impact the study of religious or spiritual phenomenon.